Is Microfracture Alone Enough?

نویسندگان

چکیده

The technique of microfracture (MFX) was first performed 40 years ago and served for many as the main procedure repairing cartilage defects. There is a need to improve microfractures because regenerated differs from original histological aspect; it less hyaline more fibrocartilaginous. In addition, importantly, benefits do not persist long-term results are unsatisfactory. Adjunctive treatments include platelet-rich plasma (PRP), cell-free-based scaffolds, adipose-derived mesenchymal stem cells (ADSCs), bone marrow aspirate concentrate (BMAC). aim this review provide an overview perspective available data regarding MFX principal adjunctive recent also challenge traditional procedure. We found that cell-free plasma, concentrate, although they relatively novel therapies, showed great potential maintained their clinical longer periods time compared alone. As chitosan-based therapy cells, we were able form definitive conclusion. believe show promising results, future research should be done on each topic discussed. Moreover, investigators involved in stimulation techniques focus conducting prospective comparative studies, performing second-look arthroscopy, rely single enhancement can adequately with

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ژورنال

عنوان ژورنال: Applied sciences

سال: 2021

ISSN: ['2076-3417']

DOI: https://doi.org/10.3390/app11167309